Research Fellow - Lab Medicine and Pathology

Mayo ClinicRochester, MN
$67,283 - $78,711

About The Position

The candidate will be working under the mentorship of Dr. Maia and Dr. Harrington in a joint project to define transcriptional dependencies associated with serous (p53 Aberrant) endometrial cancer.

Requirements

  • Experience with genomics techniques such as ATAC-seq, RNA-seq, ChiP-seq, CUT&RUN is preferred.
  • Experience within vivo preclinical models of oncology is also preferred.

Responsibilities

  • Cultivate mammalian cell cultures, primarily intestinal organoid/tumoroid models
  • Derive and establish normal and cancer organoid lines from patient samples
  • Design and conduct drug screenings and evaluate the efficacy of novel therapeutics in preclinical organoid models.
  • Use reporter expressing organoid models to assess cell state dynamics, in response to various compounds and drug candidates, using flow cytometry analysis.
  • Conduct a wide range of molecular biology techniques, such as DNA/RNA extraction, PCR, qPCR, cloning, western blotting and chromatin immunoprecipitation (ChiP).
  • Interpret, present, and document experiments based on generated data to investigators
  • Maintain and report accurate records of data

Benefits

  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
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