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Profluent - Emeryville, CA

posted 5 days ago

- Entry Level
Emeryville, CA
Publishing Industries

About the position

We're currently seeking a creative, passionate, and detail-oriented individual to join our team. You will develop, automate, and execute high throughput cell-based and in vitro gene editing assays. This position is critical in our quest to develop powerful and novel gene editing technology to address major unmet needs in therapeutics and beyond. This is an excellent opportunity to shape the future of AI-driven protein design and to work cross-functionally with a diverse team of experts across machine learning, protein engineering, cell biology, and gene editing.

Responsibilities

  • Develop, execute and automate cell-based and in vitro gene editing assays, using a variety of assay readouts, including flow cytometry, NGS and fluorescence
  • Perform mammalian cell culture and transfection for arrayed and pooled screening
  • Design and execute low throughput and high throughput plasmid cloning campaigns for construction of protein libraries
  • Precisely track and document experimental samples, assay data, and results
  • Analyze experimental data and interpret results
  • Present experimental results to colleagues in team and cross-team meetings
  • Contribute to lab maintenance and adhere to EHS standards

Requirements

  • BS or MS in Molecular Biology, Biochemistry, Cell Biology, or a related field
  • 2-6 years of biotechnology industry research experience or equivalent academic experience
  • Extensive, hands-on experience with mammalian cell culture and molecular biology
  • Excellent communication skills and the ability to work collaboratively across interdisciplinary teams
  • Strong organizational skills to accurately track laboratory samples and experimental data

Nice-to-haves

  • Experience with CRISPR and/or mammalian cell-based gene editing assays
  • Experience with high throughput screening workflows
  • Experience with process development for automation workflows
  • Experience processing and analyzing large experimental datasets
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