St. Jude Children's Research Hospitalposted about 1 month ago
Full-time • Entry Level
Memphis, TN
Religious, Grantmaking, Civic, Professional, and Similar Organizations

About the position

A postdoctoral research associate position is available in the lab of Anand G. Patel. Our lab is interested in the control and regulation of intratumoral heterogeneity within pediatric cancers. In prior work, we have developed tools and methods to map the cellular diversity of pediatric tumors by adapting single-cell sequencing techniques to archival frozen tumors. In that work, we identified powerful developmental patterns that drive malignant cell state diversity. In rhabdomyosarcoma, we have identified key cell states that are drug-tolerant and drive recurrence. In current projects, we are working to elucidate how individual cell state identities are dynamically regulated during therapy and metastasis.

Responsibilities

  • Work and lead a multidisciplinary team focused on the study of rhabdomyosarcoma.
  • Develop skills in cell biology, single-cell sequencing, preclinical modeling, and epigenetic profiling.
  • Design and perform experiments, coordinate collaborations, and prepare manuscripts for publication.

Requirements

  • Ph.D. in biology or computational biology.
  • Strong background in cancer biology, cell biology, or related fields.

Nice-to-haves

  • Experience in cell culture, epigenomics/transcriptomics, Western blotting, flow cytometry, and/or cell culture.
  • Expertise in 3D cell culture, xenografting, and/or single-cell sequencing.
  • Bioinformatic experience.

Benefits

  • Competitive salary starting at $72,500 a year.
  • Comprehensive benefits and generous relocation assistance.
  • Access to professional development opportunities, including training in scientific communication, manuscript publication, and grant writing.
  • A vibrant postdoc community that supports a well-balanced life.
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