About the position
At Exact Sciences, we are dedicated to changing how the world prevents, detects, and guides treatment for cancer. As a Bioinformatics Scientist I, you will play a crucial role in this mission by working on multiple projects that are moderate to complex in scope. With limited guidance from more experienced scientists, you will be responsible for planning and executing bioinformatics analyses, making detailed observations, and interpreting results. This position requires you to work both independently and collaboratively within a team setting, primarily focusing on Research and Development projects that contribute to the development of diagnostic assay products. In this role, you will conduct analyses across various product or technology areas, identifying problems and discrepancies as they arise. You will independently plan and analyze results from bench-level experiments, manage bench-generated data, and bioinformatics outputs within high-performance computing (HPC) or cloud computing environments. Your technical expertise will be essential in providing input for project planning and experimental design, as well as in preparing scientific abstracts, reports, and documentation for project meetings and publications. As a technical lead, you will generate and communicate development plans for critical project aspects, evaluate the impact of nonconforming data, and identify trends in study data. You will also be responsible for maintaining a clear and consistent lab notebook, following all legal, ISO, and QSR requirements. Your ability to present results and defend scientific ideas at various meetings will be vital, as will your capacity to collaborate effectively with team members and contribute to a positive, open environment built on trust. This position requires strong analytical, problem-solving, and decision-making skills, as well as the ability to manage multiple projects with frequently changing priorities. You will be expected to uphold the company's mission and values through accountability, innovation, integrity, quality, and teamwork, while also supporting the company's Quality Management System policies and procedures. Regular and reliable attendance is essential, and you will need to demonstrate an inclusion mindset in all interactions.
Responsibilities
- Conduct analyses within several product or technology areas and identify problems and discrepancies.
- Independently plan and analyze results of bench level experiments within several product or technology areas.
- Manage bench-generated data and bioinformatics outputs within high performance computing (HPC) or cloud computing environment.
- Utilize and apply methods or technologies effectively and provide ideas for new techniques, when appropriate.
- Maintain knowledge of technological industry developments that could assist in completion of an assignment or aid in the development of new processes or procedures.
- Provide technical input and participate in decisions affecting project planning and experimental design.
- Prepare and provide information and data for scientific abstracts/conferences/project meetings/publication.
- Generate, document, and communicate development plans for critical aspects of a project.
- Participate in the development of research plans and experimental outlines.
- Prepare detailed technical procedures, protocols, and reports.
- Evaluate impact of nonconforming data to product or process.
- Identify and address trends in study data.
- Prepare and approve written reports.
- Lead identification of areas for process improvements.
- Maintain lab notebook in a clear, complete, and consistent manner, following all legal, ISO, and QSR requirements.
- Prepare reports and documentation providing the analysis or summarization of results, outcomes and next steps to supervisor, technical teams/groups, or project teams.
- Present results and defend scientific ideas and findings at data meetings, group meetings, project team meetings, and/or departmental meetings; provide technical input as needed.
- Demonstrate technical proficiency and knowledge, scientific creativity, collaboration with others, and independent thought and ability to provide insights and defend scientific ideas.
- Work on problems of diverse and complex scope in which analysis of data requires evaluation of identifiable factors.
- Exercise judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions.
- Work on individual assignments and with project team members as appropriate to meet department and project objectives.
- Work within project timeframes that are established collaboratively by team members.
- Act as technical leader for one or more projects that are moderate to complex in scope.
- Exercise discretion and independent judgement within broadly defined practices and policies in: selecting methods, techniques and evaluation criteria for obtaining and interpreting results; analyzing data and presenting findings in a professional and knowledgeable manner.
- Promote an open, collaborative environment built on trust to foster positive teamwork.
- Assist in planning and recommendation of activities that account for prioritization of organizational and department goals.
- Ability to train and mentor bioinformatics associates.
- Ability to organize, present, and convey moderate problems or issues.
- Ability to communicate clearly with supervisor and group members.
- Demonstrate excellent presentation.
- Ability to collaborate, work effectively and contribute within team, department, and cross functional teams.
- Demonstrate strong attention to detail skills.
- Ability to effectively work on several varied projects at one time, with frequent changing priorities.
- Demonstrate excellent analytical, problem solving and decision-making skills.
- Apply sound technical knowledge and ability gained through experience and/or learning.
- Apply previous knowledge and outcomes to new and valuable problems (able to make predictions based on a deep understanding of the fundamental nature of the inputs into a decision or action).
- Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
- Support and comply with the company's Quality Management System policies and procedures.
- Maintain regular and reliable attendance.
- Ability to act with an inclusion mindset and model these behaviors for the organization.
Requirements
- PhD in bioinformatics, computational biology, computer science, mathematics, or related field; or Master's degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 4 years of experience in lieu of a PhD; or Bachelor's degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 6 years of experience in lieu of PhD.
- 1+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry.
- Extensive experience in Linux-based HPC or cloud computing environments and associated tools.
- Ability to write custom code in at least three programming or scripting languages.
- Knowledge of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics.
- Working knowledge of statistical and mathematical methods in biology/genetics/genomics, including experience with statistical software, such as JMP or R.
- Basic computer skills to include Internet navigation, Email usage, and word processing.
- Proficient in Microsoft Office to include Excel, Word, and PowerPoint.
- Demonstrated ability to perform the essential duties of the position with or without accommodation.
- Authorization to work in the United States without sponsorship.
Nice-to-haves
- 2+ years of industry or academic experience, post doc.
- Experience in an FDA-regulated environment, ideally in medical device development.
- Experience in a biotech manufacturing environment, preferably in an GMP and/or ISO environment.
Benefits
- Paid parental leave
- Health insurance
- Dental insurance
- Paid time off
- Vision insurance
- Retirement plan
