The Child First model is an evidence-based, two-generation intervention that works with very vulnerable young children (prenatal through age 5 years) and their families, providing intensive, home-based services to decrease the incidence of serious mental health problems, developmental and learning disabilities, and abuse and neglect. Child First provides (1) a psychotherapeutic, dyadic intervention to strengthen the parent-child relationship, and (2) care coordination to connect the family to needed services and supports. Child First has been recognized as an evidence-based home visiting model by the U.S. Department of Health and Human Services (HHS) under the Maternal, Infant, and Early Childhood Home Visiting (MIECHV) Program and rated “Effective” by the National Registry for Effective Programs and Practice (NREPP) of the Substance Abuse and Mental Health Service Administration (SAMHSA).