Organic and Conjugation Chemist

Amgen • Thousand Oaks, CA

3d • Hybrid

About The Position

The Hybrid Modality Group in the Complex Biologics & Strategic Tech Alliance Department of LMD & RDS at Amgen is seeking a highly motivated scientist in the field of chemical conjugation to join us in the state-of-the-art research facility at the Amgen headquarters campus located in Thousand Oaks, CA . The qualified candidate will work at the interface of synthetic chemistry, biochemistry, and chemical biology, and apply their chemical synthesis skills in developing new hybrid therapeutics and to support the advancement of drug discovery programs

Requirements

• Master's Degree Or Bachelor's Degree and 2+ years of relevant experience OR Associate’s degree and 4 years of relevant experience OR High school diploma / GED and 6 years of relevant experience
• Demonstrated proficiency in organic synthesis including designing, executing, and optimizing chemical reactions
• Experienced in various purification and analytical techniques including chromatography methods (e.g. HPLC, RP HPLC chromatography) and structural determination methods (e.g. NMR, MS)
• Demonstration of good lab practices, with particular attention to safety
• Strong written and verbal communication skills
• Ability to work comfortably within a dynamic team of scientists and engineers with diverse technical and cultural backgrounds

Nice To Haves

• Experience in peptide synthesis is preferred
• Experience with protein conjugation is preferred

Responsibilities

• Synthesis, purification and characterization of antibody, protein, peptide conjugates for potential clinical drug development.
• Synthesis, purification and characterization of small molecule payloads and linkers for development of novel antibody-drug conjugates.
• Operate and maintain standard lab equipment.
• Document experimental plans and procedures with attention to detail in a timely manner.
• Review, analyze, and interpret scientific data and results; and provide regular updates, documentation, and/or communication on project results.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Associate degree