About the position
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. At Eli Lilly and Company, our Global Pharmacokinetics/Pharmacodynamics and Pharmacometrics team is dedicated to advancing the discovery and development of innovative medicines through interdisciplinary collaboration and the application of innovative quantitative science and technology. Our vision is to be leaders in model-informed drug discovery, development, and decision-making, cultivating a community of exceptional scientists who transform insight into impact, improving global health. We are seeking a creative, motivated, and eager Pharmacometrics Scientist to join our team. As a functional leader in clinical development, you will play a pivotal role from candidate selection through clinical post-drug approval.
Responsibilities
- Advocate for Model-Informed Drug Development (MIDD) approaches both internally and externally.
- Drive significant advancements in clinical drug development programs through innovative population PK/PD modeling and simulation approaches.
- Engage with regulatory agencies to support drug development strategies based on modelling and simulation.
- Provide PK/PD & Pharmacometrics scientific leadership to project teams to guide the selection of the right target, molecule, dose, patient population, and development approaches.
- Influence decision-making through collaboration on cross-functional teams, including close collaboration with discovery PMx.
- Mentor other scientists and collaborate with academia.
- Represent the group to increase visibility externally through key publications, active leadership in key scientific organizations, industry trade groups, or consortia.
Requirements
- PhD in relevant scientific field such as pharmacometrics, pharmacology, biological/pharmaceutical sciences, bioengineering, biostatistics, computer science/engineering, data science, or a related field.
- Training or experience in population PK modeling and exposure-response modeling.
Nice-to-haves
- The level of the position will be determined based on the years of experience in the field.
- Proficiency in using NONMEM (or Monolix) and R. Experience with other relevant modeling and simulation software (e.g., Julia, Phoenix NLME, MATLAB, Simbiology, SIMCYP, WinNonLin, etc.) will be highly appreciated.
- Demonstrated excellent communication skills with the ability to effectively convey theories and concepts related to the pharmacometrics field to individuals who may not be familiar with the subject.
- Adept at working with cross-functional colleagues, demonstrating strong teamwork and the ability to create collaborative effects within the team.
- Strong self-management and organizational skills.
- Experience supervising other scientists is preferred but not required.
Benefits
- Eligibility to participate in a company-sponsored 401(k); pension.
- Vacation benefits.
- Eligibility for medical, dental, vision and prescription drug benefits.
- Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts).
- Life insurance and death benefits.
- Certain time off and leave of absence benefits.
- Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).
